Aphasia Neuroplasticity Review

Supplementary Table S7. Imaging: Methodology part 2

StudyAcquisitionPreprocessingModel fittingRegistrationNotes
Weiller et al. (1995) Y (axial; field of view = 5.4 cm; perisylvian only) Y Y Y
Belin et al. (1996) Y (7 transaxial slices 12 mm apart) Y Y Y
Ohyama et al. (1996) N (91 mm field of view; coverage limitations not stated) Y Y N (lesion impact not addressed)
Heiss et al. (1997) Y (whole brain) Y Y N/A
Karbe et al. (1998) Y (whole brain) Y Y N/A
Cao et al. (1999) Y (axial, perisylvian only) Y N (first level cross-correlation analysis unclear) N/A
Heiss et al. (1999) Y (whole brain) Y Y N/A
Kessler et al. (2000) Y (whole brain) Y Y N/A
Rosen et al. (2000) Y (whole brain) Y Y Y 1 patient scanned on different PET scanner, and not scanned with fMRI; controls had different fMRI sequence to patients
Blasi et al. (2002) Y (whole brain) Y Y N (not described)
Leff et al. (2002) Y (whole brain) Y Y Y
Blank et al. (2003) Y (whole brain) Y Y Y
Cardebat et al. (2003) Y (whole brain) Y Y N (lesion impact not addressed)
Sharp et al. (2004) Y (whole brain) Y Y Y
Zahn et al. (2004) Y (whole brain) Y Y N/A
Crinion & Price (2005) Y (whole brain) Y Y Y
de Boissezon et al. (2005) Y (whole brain) Y Y N (lesion impact not addressed; minimal due to lesions being small and subcortical)
Connor et al. (2006) Y (whole brain) Y Y Y
Crinion et al. (2006) Y (whole brain) Y Y Y Two different scanners used for patients, but not for controls
Saur et al. (2006) Y (whole brain) Y Y Y
Meinzer et al. (2008) Y (whole brain) Y Y Y
Raboyeau et al. (2008) Y (whole brain) Y Y N (lesion impact not addressed)
Richter et al. (2008) Y (whole brain) Y Y N (lesion impact not addressed)
de Boissezon et al. (2009) Y (whole brain) Y Y N (lesion impact not addressed)
Fridriksson et al. (2009) Y (whole brain) Y Y Y Sparse sampling
Menke et al. (2009) Y (whole brain) Y Y Y
Specht et al. (2009) Y (whole brain) Y Y Y
Warren et al. (2009) Y (whole brain) Y Y Y Two different scanners used for patients, but not for controls
Chau et al. (2010) Y (whole brain) Y Y N (lesion impact not addressed)
Fridriksson (2010) Y (whole brain) Y Y Y Sparse sampling
Fridriksson et al. (2010) Y (whole brain) Y Y Y Sparse sampling
Sharp et al. (2010) Y (whole brain) Y Y Y
Thompson et al. (2010) Y (whole brain) Y Y Y
Tyler et al. (2010) Y (whole brain) Y Y Y Sparse sampling
van Oers et al. (2010) Y (whole brain) Y Y Y Breath holding scan also done to measure hemodynamic responsiveness
Papoutsi et al. (2011) Y (whole brain) Y N (lacks explanation of event durations) Y
Sebastian & Kiran (2011) Y (whole brain) Y N (only correct trials are included but it is not stated how incorrect trials were modeled; in general, it is not stated whether the control events were modeled at all) Y
Szaflarski et al. (2011) Y (whole brain) Y Y N (lesion impact not addressed)
Tyler et al. (2011) Y (whole brain) Y N (lacks explanation of event durations) Y
Weiduschat et al. (2011) Y (whole brain) Y Y Y
Allendorfer et al. (2012) Y (whole brain) Y N (no description of HRF model, which is important given sparse sampling design) N (lesion impact not addressed) Sparse sampling
Fridriksson et al. (2012a) Y (whole brain) Y N (not described clearly) Y Sparse sampling
Fridriksson et al. (2012b) Y (whole brain) Y Y Y Sparse sampling; 26 patients were also scanned with arterial spin labelling
Marcotte et al. (2012) Y (whole brain) Y Y N (lesion impact not addressed)
Schofield et al. (2012) Y (mostly whole brain but convexity or cerebellum excluded in some participants) Y Y Y
Wright et al. (2012) Y (whole brain) Y Y Y Sparse sampling
Szaflarski et al. (2013) Y (whole brain) Y Y Y
Thiel et al. (2013) Y (whole brain) Y Y N (lesion impact not addressed)
Abel et al. (2014) Y (whole brain) Y Y N (lesion impact not addressed)
Benjamin et al. (2014) Y (whole brain) N (not described) N (not described clearly) N (lesion impact not addressed)
Brownsett et al. (2014) Y (whole brain) Y N* (consistent linear order of listening and repetition trials could make it difficult to disentangle hemodynamic responses to listening and repeating trials) Y Sparse sampling; different task structure in controls (two repetition trials per listening trial) raises concerns about comparisons between groups
Mattioli et al. (2014) N (unclear; number of slices not stated) Y N (model fitting of noise "bip" not clearly described) Y
Mohr et al. (2014) Y (whole brain) Y Y N (lesion impact not addressed) Sparse sampling
Robson et al. (2014) Y (whole brain) Y Y Y Spin echo fMRI to minimize ATL dropout
Szaflarski et al. (2014) Y (whole brain) Y Y Y
van Hees et al. (2014) Y (whole brain) Y Y N (lesion impact not addressed) Slow event-related design; sparse sampling
Abel et al. (2015) Y (whole brain) Y Y N (lesion impact not addressed)
Kiran et al. (2015) Y (whole brain) Y Y Y Controls were run on two different sets of parameters, neither of which was the same as the patients
Sandberg et al. (2015) Y (whole brain) Y Y Y
Geranmayeh et al. (2016) Y (whole brain) Y Y Y Sparse sampling; mini-blocks of 2-4 trials
Griffis et al. (2016) Y (whole brain) Y Y N (lesion impact not addressed)
Sims et al. (2016) Y (whole brain) Y Y Y No smoothing
Darkow et al. (2017) Y (whole brain) Y Y Y Sparse sampling
Geranmayeh et al. (2017) Y (whole brain) Y Y Y Sparse sampling; mini-blocks of 2-4 trials
Griffis et al. (2017a) Y (whole brain) Y Y Y
Griffis et al. (2017b) Y (whole brain) Y Y Y
Harvey et al. (2017) Y (whole brain) Y Y N (lesion impact not addressed)
Nardo et al. (2017) Y (whole brain) Y Y Y
Nenert et al. (2017) Y (whole brain) Y Y N (lesion impact not addressed)
Qiu et al. (2017) Y (whole brain) N (not described) N (no description of model fitting) N (not described)
Skipper-Kallal et al. (2017a) Y (whole brain) Y N* (not stated but see Skipper-Kallal et al. (2017b)) Y At each voxel, individuals with lesions to that voxel were excluded from analysis
Skipper-Kallal et al. (2017b) Y (whole brain) Y N* (entire phases where picture was displayed modeled as covert and overt naming; difficult to separate phases due to timing) Y
Dietz et al. (2018) Y (whole brain) Y N (no description of HRF model, which is important given sparse sampling design) N (lesion impact not addressed) Additional methodological details in Dietz et al. (2016)
Hallam et al. (2018) Y (whole brain) Y Y Y Interleaved silent steady state imaging
Nenert et al. (2018) Y (whole brain) Y Y N (lesion impact not addressed) Scanner identity appropriately included as covariate
Pillay et al. (2018) Y (whole brain) Y Y Y
Szaflarski et al. (2018) Y (whole brain) Y Y Y
van de Sandt-Koenderman et al. (2018) Y (whole brain) Y Y N (lesion impact not addressed)
van Oers et al. (2018) Y (whole brain) Y Y Y Not all participants scanned at each time point; the number scanned at each time point is not stated
Barbieri et al. (2019) Y (whole brain) Y Y Y 2 runs before treatment and 2 runs after treatment; each pair of runs took place on two separate days (1-7 days apart)
Johnson et al. (2019) Y (whole brain) Y N* (unclear whether there was sufficient resting data to allow the key contrast to be computed) Y
Kristinsson et al. (2019) Y (whole brain) Y Y Y Sparse sampling
Purcell et al. (2019) Y (cerebellum excluded) Y N* (not feasible to separate closely spaced instruction, word, and letter/response, especially when responses will be compared to rest) Y
Sreedharan et al. (2019b) Y (whole brain) Y N* (event timing will make conditions difficult to disentangle) N (lesion impact not addressed)
Hartwigsen et al. (2020) Y (whole brain) Y Y N (lesion impact not addressed)
Stockert et al. (2020) N (whole brain; TE = 96 ms questionable) Y Y Y

Acquisition = Are the imaging acquisition parameters, including coverage, adequately described and appropriate?; Preprocessing = Is preprocessing and intrasubject coregistration adequately described and appropriate?; Model fitting = Is first level model fitting adequately described and appropriate?; Registration = Is intersubject normalization adequately described and appropriate?; ATL = anterior temporal lobe; fMRI = functional magnetic resonance imaging; HRF = hemodynamic response function; N = No; N/A = N/A—no intersubject normalization.; PET = positron emission tomography; Y = Yes; Yellow underline = minor limitation; Orange underline/* = moderate limitation.